PROCEDURES APPLIED IN ISTANBUL MEMORIAL HOSPITAL ASSISTED REPRODUCTIVE TECHNOLOGIES & REPRODUCTIVE GENETICS CENTER

Istanbul Memorial Hospital Assisted Reproduction Technologies & Reproductive Genetics Center was established in 2000. A mission of our center is to provide various comprehensive and individualized medical options for the treatment of infertile patients in order to realize their desire of having a baby and being a real family. Since the establishment of our center, the endeavour of turning  hopes of infertile patient into a reality has been enforcing us to be a pineer of assisted reproductive technologies in a region Asia and Europe coming together.  

Istanbul Memorial Hospital Assisted Reproduction Technologies & Reproductive Genetics Center has well educated and most experienced medical doctors, embrylogists and geneticists, dedicating theirselves to help infertile patients. We have been applying lots of firsts including the first ICSI pregnancies, getting live birth from blastocyste transfer for the first time and first pregnancy following embryo biopsy and pre-implantation genetic testing for several single gene disorders in Turkey.

Istanbul Memorial Hospital Assisted Reproduction Technologies & Reproductive Genetics Center is an independent facility which includes a internationally certified andrology laboratory, and embryology (IVF) laboratory and an accredited genetics center.

We are a leader in ART in Turkey and provide a full range of infertility and reproductive endocrinology and genetics applications including:

APPLIED PROCEDURES IN OUR CENTER

• Clinical Applications

• Approach to the Infertile Couple

• Evaluation of the female partner

• Infertility tests and their evaluation

• Conventional methods for infertility treatment (Ovulation induction, intrauterine insemination)

• Ovulation Induction and monitoring in Assisted Reproductive Technologies

• Trans-vaginal Oocyte Collection

• Embryo transfer

Urology

• Evaluation of the male partner

• Testicular Sperm Aspiration (TESA)

• Testicular Sperm Extraction (TESE)

• Testicular Sperm Extraction with Micro-Surgical Method (Micro-dissection TESE)

• Micro Epididymal Sperm Aspiration (MESA)

Laboratory Applications

   Embryology laboratory

• Ovum Collection (OPU)

• Preparation for insemination

• ICSI (Intra-cytoplasmic sperm injection)

• In vitro fertilization (IVF)

• IMSI (Intra-cytoplasmic Morphologically-selected Sperm Injection)

• Embryo culture systems (Endometrial co-culture)

• Development, Control and Evaluation of the embryo

• Embryo transfer

• AHA (Assisted hatching)

• Embryo defragmentation procedure

• Procedures for Polar body, blastomere and trophectoderm biopsy

• Embryo freezing procedures

• Slow freezing

• Vitrification

   Andrology laboratory

• Sperm evaluation techniques

• Sperm preparation methods for IUI, ICSI and IVF procedures

• Methods for obtaining sperms with operational procedures

• Sperm morphology evaluation by

        - Spermac staining

        - Motile sperm organellar morphology examination (MSOME)

• Sperm function tests

       - Hypo-osmotic swelling (HOS) test

       - Hemi-zona assay

       - Antisperm antibody testing

• Sperm DNA integrity tests

       - Acridine orange staining

       - TUNEL assay

• Freezing/thawing techniques for sperm and testicular tissue

• Sperm preparation for sperm FISH and Y-deletion studies

   Genetic laboratory

• Cell cultures of short duration (peripheral blood) and chromosomal analyses

• Cell cultures of long duration (CVS, amniotic fluid, abort material, skin tissue) and chromosomal analyses

• Fluorescence In Situ Hybridization (FISH) analysis with specific probes Sperm FISH analysis

• Sperm FISH analysis

• DNA isolation

• Polimerase Chain Reaction (PCR) applications (Y-Chromosome micro-deletion analysis Cystic Fibrosis mutation analysis)

• DNA Sequencing applications

• Pre-implantation Genetic Diagnosis for single gene disorders and/or HLA typing

• Pre-implantation Genetic Diagnosis for chromosomal abnormality